I'm a healthly 45 year old female and will be 46 by the time baby is born. What are the risks of having a baby after 45?

The risks are two-fold. Firstly, there is a higher risk of having a baby with Down's syndrome (trisomy 21) which at 45 is around 1:25. Secondly, you have a high risk of venous thrombosis (blood clot in your legs or lungs), high blood pressure and diabetes. But despite this depressing news, more and more women are having babies in their 40s and with careful monitoring the great majority have successful pregnancies and healthy babies.
How likely is it that my baby will have Down''s syndrome?

The risk of having a baby with Down''s syndrome is related to your age, although parents of any age can have a Down''s child. It is not related to how many children you have had, whether you have a new partner, or to drugs that you might have taken at or around the time of conception.

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