Can pain-killing drugs be taken in pregnancy?

We generally advise that any drugs are avoided in the first trimester of pregnancy because at this stage the baby''s organs are developing. Having said this, there is no evidence that paracetamol (acetaminophen) taken in normal doses in harmful, nor is it if in combination with mild opiates such as codeine and dextropropoxyphene. Unless there is a clear indication for them, non steroidal drugs such as therapeutic doses of aspirin, indomethacin and similar drugs should be avoided. Low dose aspirin (75mg/day), for treating other conditions, is considered as safe.
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